Spicy Southern Cheesy Chicken Spaghetti Casserole Recipe

If you’re craving a dish that brings together a bold kick, creamy indulgence, and comforting Southern vibes all in one, you simply must try this Spicy Southern Cheesy Chicken Spaghetti Casserole. It’s a beautiful medley of tender chicken, perfectly cooked spaghetti, melty sharp cheddar, and a tantalizing spice blend that wakes up your taste buds. This casserole isn’t just dinner; it’s a cozy, flavorful hug on a plate that’s perfect for any night you want to feel like you’re being treated to something truly special and satisfying.

Ingredients You’ll Need

These ingredients are straightforward yet pack a punch in both flavor and texture. Each component plays an essential role, from the juicy chicken breasts to the creamy soup and zesty spices, creating a dish that’s rich, hearty, and vibrant.

• Boneless, skinless chicken breasts: The star protein that stays tender and juicy when cooked just right.
• Spaghetti: Provides that perfect al dente base to soak up all the cheesy, spicy goodness.
• Sharp cheddar cheese: Delivers a creamy, tangy richness that melts beautifully over the casserole.
• Fresh bell peppers: Add a gentle crunch and a pop of color to brighten the dish.
• Cream of chicken soup: Acts as a velvety binder, melding flavors and keeping everything moist.
• Paprika: Brings a warm, smoky note that complements the Southern style perfectly.
• Cayenne pepper: Gives the casserole its signature spicy kick without overwhelming.
• Garlic powder: Enhances all the other flavors with its deep, savory aroma.
• Green onions: Used fresh on top for a crisp, refreshing finish.

How to Make Spicy Southern Cheesy Chicken Spaghetti Casserole

Step 1: Prep and Cook the Chicken

Start by preheating your oven to 350°F (175°C) and greasing a large casserole dish to prevent sticking and encourage that golden crust later. Then, cook your chicken breasts over medium heat for about 6 to 7 minutes on each side. You want them beautifully golden outside but juicy and cooked through inside. This step creates a flavorful, tender foundation that will shine in your casserole.

Step 2: Boil the Spaghetti

While your chicken is cooking, bring salted water to a boil and cook the spaghetti until it’s perfectly al dente, around 8 to 10 minutes. This ensures the pasta won’t get mushy during the bake but will soak up all the creamy sauce and spices wonderfully. Drain and set it aside.

Step 3: Combine Ingredients

In a large bowl, shred your cooked chicken and mix it with the drained spaghetti, cream of chicken soup, chopped bell peppers, paprika, cayenne pepper, garlic powder, and half of the shredded sharp cheddar cheese. This combination creates the heart of the Spicy Southern Cheesy Chicken Spaghetti Casserole, with vibrant colors and layers of flavor ready to shine.

Step 4: Assemble and Bake

Pour and spread the mixture evenly into your prepared casserole dish. Top it generously with the remaining sharp cheddar cheese. This layer adds that irresistible golden, bubbly cheese crust everyone loves. Bake the casserole for 25 to 30 minutes until it’s piping hot, bubbly, and beautifully golden brown on top.

Step 5: Rest and Garnish

Once baked, allow your casserole to rest for about 5 minutes. This step helps everything set up nicely for easier serving. Then sprinkle the fresh sliced green onions on top for a slight crunch and fresh zesty contrast that balances the creamy, spicy base.

How to Serve Spicy Southern Cheesy Chicken Spaghetti Casserole

Garnishes

Simple is best here. Fresh sliced green onions add the perfect mild sharpness and vibrant green color that livens up each serving. You can also sprinkle a dash of extra paprika for a visually appealing pop of red and a hint more smoky depth.

Side Dishes

This casserole is hearty, but pairing it with a crisp green salad or some roasted seasonal vegetables will round out the meal beautifully. A cool cucumber salad or tangy coleslaw works wonders to balance the heat and richness.

Creative Ways to Present

Consider serving the casserole family-style right from the baking dish for that warm, inviting Southern comfort feel. Or scoop individual portions into small ramekins, topped with a little extra cheese and scallions, then broil briefly for a fancy, golden finish perfect for dinner guests.

Make Ahead and Storage

Storing Leftovers

Store leftover Spicy Southern Cheesy Chicken Spaghetti Casserole in an airtight container in the refrigerator for up to 3 days. The flavors actually deepen overnight, making leftovers even better in some ways.

Freezing

If you want to save some for later, this casserole freezes beautifully. Transfer cooled portions into freezer-safe containers or bags and freeze for up to 2 months. Thaw overnight in the fridge before reheating.

Reheating

To reheat, warm individual portions in the microwave for 2 to 3 minutes, or oven bake at 350°F (175°C) for 15 to 20 minutes until thoroughly heated and bubbly again. You can add a sprinkle of cheese on top before heating for a fresh melt.

FAQs

Can I use rotisserie chicken instead of cooking chicken breasts?

Absolutely! Rotisserie chicken is a fantastic shortcut that adds extra flavor and saves time. Just shred it and proceed with the recipe as usual.

Is there a way to make this casserole less spicy?

Yes, simply reduce or omit the cayenne pepper if you prefer a milder dish. The paprika will still give a wonderful warm flavor without the heat.

Can I substitute the sharp cheddar cheese with another kind?

Sharp cheddar is ideal for its tang and meltiness, but you can try Monterey Jack, Colby, or even a mozzarella-cheddar blend for a different cheesy twist.

What if I don’t have cream of chicken soup?

You can make a quick homemade substitute with a white sauce (béchamel) seasoned with chicken broth, or use cream of mushroom soup for a slightly different but delicious flavor.

How spicy is the Spicy Southern Cheesy Chicken Spaghetti Casserole?

It has a noticeable but balanced kick thanks to cayenne pepper, complemented by smoky paprika and garlic. You can adjust the level of heat easily to suit your taste.

Final Thoughts

There’s something truly special about the Spicy Southern Cheesy Chicken Spaghetti Casserole that makes it a go-to for comfort food lovers craving flavor and warmth. It’s hearty, easy to make, and full of personality – just like a great Southern dish should be. I can’t wait for you to try it and make it a beloved staple in your own kitchen!

Print